Ethyl acetate is mainly used as a coating solvent

Ethyl acetate is rapidly hydrolyzed to ethanol and acetic acid. When 1.6 g kg−1 ethyl acetate was injected intraperitoneally, it was rapidly hydrolyzed to acetic acid and ethanol. The biohalf-life of ethyl acetate to ethanol was found to be between 5 and 10 minutes.

Ethyl acetate (ethyl acetate sds) is easily absorbed in the mouth, skin, or after inhalation. Absorbed in the gastrointestinal tract when taken orally and in the upper respiratory tract when inhaled, it rapidly hydrolyzes to ethanol and acetic acid.

The absorbed ethyl acetate is also rapidly hydrolyzed into ethanol and acetate in the blood. If the ethanol produced after the absorption and hydrolysis of ethyl acetate exceeds the metabolism and elimination of ethanol, the concentration of ethanol in the blood will increase.

Ethyl acetate is rapidly hydrolyzed to ethanol and acetic acid. When 1.6 g kg−1 ethyl acetate was injected intraperitoneally, it was rapidly hydrolyzed to acetic acid and ethanol. The biohalf-life of ethyl acetate to ethanol was found to be between 5 and 10 minutes. In rats, at doses higher than 1.6 g kg−1, the rate of hydrolysis exceeds the rate of ethanol oxidation, resulting in the accumulation of ethanol in the vascular system.


Ethanol produced during the metabolism of ethyl acetate is excreted through exhaled air and urine.

The interaction of ethyl acetate with toluene reduced its toxicity, while the combination of ethyl acetate with ethanol, ethylene glycol, morpholine, propylene oxide, propylene glycol, or formalin reduced the LD50 value of ethyl acetate.


Ethyl acetate is mainly used as a coating solvent for (1) coatings, varnishes and varnishes; (2) Extraction solvents for various processes, including the decaffeination of coffee and tea; (3) process solvents in the pharmaceutical industry; And (4) carrier solvents for printing inks, adhesives, and nail polish. It is also used in the manufacture of artificial leather and perfume, as well as certain household products, including aircraft glue, paint and nail polish removers.


Lillian Tong

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